difficile

[dif-i-seel, dee-fee-seel]

adjective

1. hard to deal with, satisfy, or please.

2. hard to do; difficult.

Word History and Origins

Origin of difficile¹

1470–80; < French < Latin difficilis difficult; dif-, facile

Example Sentences

Faecal transplants – also known as a trans-poo-tion - are already approved for treating severe diarrhoea caused by Clostridium difficile bacteria.

From BBC

But scientists noticed hints that faecal transplants for C. difficile also seemed to get rid of superbugs.

From BBC

The researchers are currently working on modifying the system to help combat Clostridioides difficile, commonly referred to as C. diff, a bacterium that can cause diarrhea and colitis, among other symptoms.

From Science Daily

The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.

From Science Daily

FMT has a 90% cure rate for C. difficile infection.

From Salon

Related Words

• ambitious 
• arduous 
• burdensome 
• challenging 
• crucial 
• demanding 
• laborious 
• onerous 
• painful 
• problematic 
• severe 
• strenuous 
• tough 
• troublesome